Systematic reviews or meta-analysis — Gram-negatives

Systematic reviews and meta-analysis focused on Gram-negative bloodstream infections (GNBSI) and interventions specifically aimed at carbapenemase-producing Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa.

With the overwhelming amount of evidence and studies being published it is almost impossible for clinicians to keep up-to-date with all the literature. Systematic reviews provide summaries of outcomes and interventions, whether they are successful or not, in one publication. 

Systematic reviews or meta-analysis for reducing GNBSI

Systematic reviews for the prevention and control of carbapenemase-producing Enterobacteriaceae , Acinetobacter baumannii and Pseudomonas aeruginosa

Healthcare associated infection outbreaks from water reservoirs

All resources were up-to-date at the time of publication. Please email nhsi.improveipc@nhs.net with any new resources for consideration.

What is a systematic review?

A systematic review is a method whereby multiple sources of published evidence about a particular clinical issue are reviewed and synthesised in a way that limits bias and presents the combined evidence from all of the sources. Systematic reviews are valuable because they present the summary of the evidence from multiple studies. They may also include a meta-analysis which uses statistical techniques to combine the data provided in several studies into a single estimate. 

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